Liverpool will be hoping to finally get their league season going when Arsenal visit Anfield on Sunday, with Raheem Sterling and Olivier Giroud looking to make it an entertaining game.
Sunderland travel to St James Park looking for a fourth straight Tyne and Wear derby win over Newcastle United, with Santiago Vergini and Paul Dummett men in form.
West Ham United entertain rock-bottom Leicester City at Upton Park this weekend with left-backs Aaron Cresswell and Paul Konchesky impressing the stats men.
Burnley travel to White Hart Lane to battle Tottenham Hotspur hoping to continue their recent good form, though defenders Jan Vertonghen and Jason Shackell could be key.
The midfield battle between in-form Ross Barkley and Victor Wanyama provides an interesting sub-plot as Everton travel to St Mary’s to battle Southampton.